Correct and consistent use of a female or male condom means you can enjoy sex while Preventing unintended pregnancy Preventing HIV and other sexually transmitted infections Lightly Lubricated Condoms Walgreens Spermicide: How To Use, Benefits, Risks & Effectiveness Condoms protect against unplanned pregnancy and most sexually transmitted infections, including HIV, gonorrhoea, chlamydia, and syphilis. Use only water or silicone based lubricant with a condom during vaginal and particularly anal sex.